Image source: Free Times
Adult exposure to cigarette smoke has been widely recognized as a risk factor for type 2 diabetes. Previous studies have found that adult smokers are 30% to 40% more likely to develop type 2 diabetes than non-smokers.
However, some researchers said that it is still unclear how early exposure to tobacco smoke affects the development of type 2 diabetes, and whether this association differs depending on the genetic susceptibility to type 2 diabetes.
The results of a preliminary study were published at the American Heart Association’s Epidemiology and Prevention Lifestyle and Cardiometabolic Sciences Conference in March this year. Exposure to tobacco smoke during fetal life and the onset of smoking in childhood or adolescence are strongly associated with the development of type 2 diabetes in adulthood, particularly in those who develop type 2 diabetes, according to a UK Biobank study of nearly half a million adults. People at high genetic risk for type 2 diabetes. .
In the study, researchers reviewed data from nearly 500,000 adults in the UK Biobank to assess exposure to tobacco during fetal life and initiation of cigarette smoking in childhood (5-14 years) or adolescence (15-17 years) Association with the development of type 2 diabetes. The polygenic risk score for type 2 diabetes was used to evaluate the possible interactive and joint effects of early exposure to tobacco and genetic susceptibility on the development of type 2 diabetes.
Participants with a genetic predisposition to type 2 diabetes and who started smoking in childhood or adolescence had the highest risk of developing type 2 diabetes among people who were exposed to tobacco before birth or started smoking in childhood or adolescence.
Compared with people who have never smoked, exposure to tobacco smoke during fetal life is associated with a 22% increased risk of developing type 2 diabetes. People who start smoking as children have twice the risk of developing type 2 diabetes. People who start smoking as teenagers have an increased risk of developing type 2 diabetes. 57%, while those who started smoking as adults had a 33% increased risk.
People who were exposed to tobacco smoke during fetal life, started smoking during childhood or adolescence, and had a high genetic risk score for type 2 diabetes compared with participants who were not exposed to tobacco smoke early in life and had a low genetic risk score for type 2 diabetes. The risk increases were 330%, 639% and 427% respectively.
Cigarette smoke contains 6,000 chemical substances, hundreds of toxic substances, and dozens of substances that are recognized as first-level carcinogens. The author calls on smokers not to underestimate the dangers of indoor smoking. According to research, cigarette smoke may increase the risk of fetal diabetes. If you must smoke, be sure to go to a smoking room, balcony and other well-ventilated places. Do not underestimate the harm of cigarettes to your family.
Article source: Exposure to tobacco before birth significantly increased risk of Type 2 diabetes in adults | American Heart Association
Tags: Unborn fetuses develop diabetes grow PeoPo Citizen News
